Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
نویسنده
چکیده
The rat brain capillary permeability coefficient was determined for 27 compounds. The relationship of permeability to octanol/water partition coefficient and molecular weight was found to be predictable for drugs with molecular weights less than 400.
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ورودعنوان ژورنال:
- Journal of medicinal chemistry
دوره 23 6 شماره
صفحات -
تاریخ انتشار 1980